POLIO VACCINATION

Polio Vaccination

Polio Vaccination

Introduction

In the last few centuries, medicine has made a considerable progress and due to this life expectancy has been increased. Vaccination termed as greatest progress in public health. After the World War II, new vaccines developed in order to keep away people from the virus which inject in childhood. This disease termed as Polio and Polio vaccines prepared to develop a specific immune response, with minimal adverse reactions on the subject to which you given. In this paper, we will discuss the two different Polio vaccinations and which vaccination is most useful to contemporary public health practice.

Discussion

Polio

Polio is a disease that can cause irreversible paralyze in less than 1% of those people who are infected. It is highly contagious and cause by three serotypes of poliovirus. It spread from person to person mainly by fecal oral route. The virus is extremely stable and can remain viable in the environment for long periods. After introducing inactivated vaccine (IPV), in many countries, this disease has been eliminated. People who are suffering from polio experienced many different health problems. These health problems are increase in muscle weakness, exhaustion; pain in joints and muscles, and few suffers from breathing problems (World Health Organization, 2004, pp. 1).

The poliovirus is more likely to occur in children from 4 to 15 years in temperate climates, in summer, and warm winter is a highly infectious disease, but fought with vaccination. The disease affects the central nervous system; moreover, it causes inflammation in the neurons of motor spinal cord and brain and leads to paralysis, muscular atrophy and often deformity. The worst cases caused as permanent paralysis or death by paralyzing the diaphragm (Ciro A. de Quadros, Jon K. Andrus, Jean-Marc Olive, and Carlyle Guerra de Macedo., 1992, pp. 239).

Lyon France, (2005), Poliovirus Vaccine Inactivated, Sanofi Pasteur Inc, Pp. 1-7

In this article, the author has discuss regarding the Poliovirus Vaccine inactivated which his produced by Sanofi Pasteur. In this article, Cross-sectional study has been carried out to see the result of the IPV. During the clinical studies, around 700 infants between 2 to 18 months old were administered with the IOPL vaccine which was using IPV schedule. IPOL suggested for the active immunization of infant such as 6 week of age and adult as well in order to prevent from the poliomyelitis induced by poliovirus Types 1, 2, and 3. Dangerous polio virus types I, II or III by cell culture in Vero cells established in human diploid cells which is the medium of filtration, ultra filtration and chromatography and production of purified virus suspension takes place. The separation of cell components is prerequisite for complete virus inactivation.

This requires several days for treatment with formaldehyde, a chemical reaction of formaldehyde with viral components that will increase the probability of the virus to eradicate. Since no infectious virus can be detected, the remaining formaldehyde removed. The test for non-inactivated virus carried in a cell culture test; the detection of the antigen content is an ELISA test carried out, ...