Evidence Synthesis Paper

The Use of Ketorolac in Postoperative Pain Management

Abstract

The Synthesis paper is based on critical analysis of nine peer reviewed articles for analyzing and determining the importance of Ketorolac in Postoperative pain management. All these articles were based on different disease management with the help of anti-inflammatory drugs such as Ketorolac and Morphine in postoperative pain management. Postoperative analgesia is one of the basic components of functional recovery after surgery. However, separating the effects of postoperative analgesia from other factors Such as the surgical technique, clinical practice, the type of analgesic follow-up and the organizational factors of the surgical team can be difficult.

The introduction of laparoscopy, and minimally-invasive Thoracoscopy surgical techniques modifying the traditional protocols are used in complex surgery. Intravenous patient-controlled analgesia and oral opioids are even epidural analgesia replacing in this type of technique.

Evaluation of the risk / benefit ratio for the selection of the proper postoperative analgesia technique depends on the severity of pain and the dynamic potential adverse effects of analgesic drugs and techniques. Demonstrating the impact of postoperative analgesia on major outcomes Such as Surgical Mortality, morbidity, or length of stay, as can be Difficult these outcomes depend on multiple and heterogeneous factors. The effect of a specific type of surgical analgesia on the entire process should be investigated on the basis of patient-oriented outcomes, Such as the quality of analgesia, adverse effects and postoperative comfort. Other areas in postoperative analgesia Which Could have an impact postoperative oncological Are those related to postoperative recurrence and chronic pain.

Table of Content

Abstractii

CHAPTER 1: INTRODUCTION1

Purpose of the study1

Aims and Objectives1

Significance of the study1

PICOT Question2

Chapter 2: LITERATURE REVIEW4

Body of Evidence (Keeper Studies 1)4

Body of Evidence (Keeper Studies 2)6

Pharmacological Properties8

Metabolism and Pharmacokinetics8

Therapeutic Applications8

Toxic effects9

Body of Evidence (Keeper Studies 3)9

Body of Evidence (Keeper Studies 4)11

Body of Evidence (Keeper Studies 5)12

Body of Evidence (Keeper Studies 6)13

Body of Evidence (Keeper Studies 7)14

Body of Evidence (Keeper Studies 8)15

Body of Evidence (Keeper Studies 9)17

CHAPTER 3: METHODOLOGY19

CHAPTER 3: METHODOLOGY19

Characteristics of the Articles19

Characteristics of Search 119

Characteristics of Search 219

Characteristics of Search 320

Characteristics of Search 420

Characteristics of Search 521

Characteristics of Search 621

Characteristics of Search 721

Characteristics of Search 822

Characteristics of Search 922

Advantages of Secondary Research22

Evidence Based Practice23

Analysis of Secondary data23

Methods of searching24

Inclusion criteria25

Exclusion criteria25

Excluding Terms25

Studies Excluded25

Ethical considerations26

CHAPTER 4 ANALYSIS AND DISCUSSION27

CHAPTER 5 CONCLUSION31

Summary Statement31

REFERENCES32

CHAPTER 1: INTRODUCTION

Purpose of the study

The purpose of the study is simple: to understand the significance of using Ketorolac as a suppressant for pain in patients suffering from acute postoperative pain. Ketorolac is compared to narcotic analgesics for pain control in patients suffering from acute postoperative pain during the 48 hours following surgery.

Aims and Objectives

The main aim and objective of this study was to evaluate the effectiveness of Ketorolac and Morphine in the postoperative pain management. Different peer reviewed articles were selected based on various surgeries and diseases such as lumbar decompression surgery, postoperative bowel function, colorectal surgery, laparoscopic surgery, Balanced analgesia after hysterectomy and Intranasal ketorolac for acute postoperative pain.

Significance of the study

This study will be beneficial in assisting people with acute pain in postoperative ...