HOST PATHOGEN INTERACTIONS

Model Hosts Used To Determine Host Pathogen Interactions

[Name of the Institute]

Model Hosts Used To Determine Host Pathogen Interactions

Introduction

The aim and objective of this essay is to discuss and analyze the Host Pathogen Interactions which are determined by model hosts.

Discussion

In the olden days the host-pathogen interaction was governed by micro-organisms which were known as the principal invaders. Int he intial years of 20th century, Smith determines the importance and necessity of host pathogen but he gave more emphasis to the microbial characteristics and signalled these characteristics responsible for developing microbial virulence. He was of the view that, pathogenic microbes possess functions of invading and defending which isolates them from non-pathogenic microbes. The research has been conducted by Smith and Zinsser on the Host Pathogen Interactions. In 1913, Smith conbducted research on microbial characteristics and gave his viewpoint (Smith, 1913, pp. 1591-1599). According to another researcher Zinsser in 1914, the term pathogenic is able to cause disease and he also asserted that virulence posses two features (Zinsser, 1914, pp. 11-27). These features are defined below:

Pathogen that is dormant hold characteristics of microbial for instance, capsules which enables steadiness in the host and aggressive that comprises toxins, etc.

However, the results of the interface between the pathogen and the host lead us to the basis of terms mutualism, commensalism, competition and parasitism. Commensalism is described as a connection between two where an organism is derive benefits and other organism neither gets any sort of benefit nor is it affected. Alternatively, mutualism is a type of relationship in which two organisms of different types derive benefits. Competition is described as an interaction in which both the organisms get debilitated and none of the organism derives any sort of benefit. While on the other hand, in the case of parasitism they derive benefits at the cost of host (Fire, et.al, 1998, pp. 806-811).

According to the postulates of Koch, there ought to be plentiful microorganisms in all. However, none of them are found in unaffected animals. Micro-organisms ought to be grown in unpolluted environment and can be isolated from the affected organism (Hajek & St. Leger, 1994, pp. 293-322). The unaffected organism has a tendency to affect the healthy organism which comes in its contact. The affected organism make separate from the rest of the inoculated and unaffected host and identified as similar to the original causative agent who was not satisfied as the behaviour of microbes was being observed.

The analysis of the observations shows no general relationship between the pathogen and the host. In recent times, microbiologists have analyzed the notion of pathogencity and virulence and have asserted that the contact between the pathogen and the host is reflected by microbial pathogenesis. The initiative of model for these organism occurred in the nineteenth century with the assistance of Charles Darwin and Gregor Mendel. The model was initiated when both of them were working on an official assignment of “Natural selection” and “Genetics of heredity” respectively. Recently, it has also been found out that the study ...