Alzheimer's Disease

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Alzheimer's Disease

Alzheimer's Disease


The paper aims to link the disfunctioning of the olfactory and the Alzheimer's disease. It attempts to emphasize on the causes of olfactory disfunctioning and associates it with the Alzheimer's disease. The paper briefly discusses the Alzheimer's disease followed by the function of olfactory. It then focuses on the relationship between Alzheimer's disease and the impariment of olfactory. It also provides tests for detecting early stages of Alzheimer's disease.


Alzheimer's Disease

Alzheimer's disease is a chronic and irreversible neurodegenerative disorder, in which alterations occur early in declarative memory, in the spatial and temporal location. In the late stages, it presents a severe dementia accompanied by motor impairment. Alzheimer's disease primarily affects the olfactory neurons. Two other indicators early Alzheimer's disease, one of which may appear 10 to 20 years before the onset of the disease obvious, is an early decline in the capacity of the memory, the second in the APOE e4 (a genetic marker) and therefore present at birth. When both are present in a person, the possibility of developing Alzheimer's is greater (Hofman, Breteler, et al., 2008).

Alzheimer's disease affects one in 25 individuals in older adults ± 65 years, increasing to 4 around 80 years, which represents a global figure of over 20 million people with this disease and given the progressive aging of the population, these figures are estimated to reach 40 million by 2040. That is why the EA, for its high incidence population acquires significant importance because of the implications that may affect the social, political and economic, to which is added a strong psychological impact on the families of those suffering (Gould, 2006).

The traditional symptoms of dementia / AD, such as memory loss, forgetfulness, understand that you have driven away from where you were going, etc.. etc.., are also common in those who do not have Alzheimer's / dementia. Therefore, if you're like me, may be a little dismayed when these symptoms are advanced, so I placed the first olfactory symptoms, to help reduce panic - I smell the essences correctly. For many older people, not just us middle-aged forgetfulness in old age is a benign condition of concern, which may not lead to something else (Cantley, 2001).

Olfactory System

Fragrant objects constantly give off volatile molecules in the air, almost all the natural scents complicated mixtures of hundreds of molecules. Orthonasally, so with the inhaled air through the nasal cavity, and an aftertaste, so you eat and drink through the oral cavity and pharynx, they go up to the so-called olfactory epithelium in the upper part of the nasal cavity, which consists of about 30 million olfactory cells (Gould, 2006).

Already in the olfactory epithelium fetuses consists of a continuous layer of Sinnesepithelzellen. In adults, it is permeated with age by non-olfactory respiratory epithelial cells. This could be a cause for the observed decrease of almost regular way of olfaction in old age. In the olfactory epithelium are ten to thirty million receptor neurons and their supporting and basal ...
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