POLYMERS

Polymers



Polymers

Inflammation induced response have been implicated in the pathogenesis of numerous diseases including cancer. Increased formation of inflammatory cytokines such as TNF-a, IL-1ß and others has been described in the pathophysiology of degenerative diseases, infections and drug-induced toxicities(Reuter et. al. 2010, pp. 105-109).

Aspirin has been shown to exert its cytotoxicity and anti-inflammatory effects through multiple mechanisms of action that may include generation of reactive oxygen species, increased oxidative stress, mitochondrial dysfunction and induction of apoptosis. However, aspirin has also been shown to protect endothelial cells from oxidative damage via nitric oxide/cGMP pathway . Aspirin has also been shown to protect ...