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There are numerous causes why enzymes have such a high specificity. The first variable is an enzyme's prime structure. A prime structure is just a blend of amino acids. There are 20 distinct amino acids that the prime structure can be conceived from. Every enzyme has a distinct alignment that the acids are put in and each one has a distinct number or amino acids. The smallest change in this structure can sway a protein's conformation and function.

Aldolase B deficiency is a rare risk-free asymptomatic situation caused by a lack of the liver enzyme.

Hereditary fructose intolerance is an autosomal ...
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