Medicine & Health

Cell Migration & Neural Crest

Neural crest cells scientifically comes from one tube that is termed as neural tube and it comes after the closure as well as the migration of the cell and this process started or arises by prescribed regions of the embryos. Embryo is actually termed as a place where they as a matter of fact differentiate or further characterized into the peripheral nervous system and along with this also to the facial skeleton as well as pigment cells. Along with the embryonic based axis, various other neural crest based populations are different and this is the reason how they actually differ in their migratory based pathways and are also different in the range of the derivatives. Along with this, those particular cells actually comes through the migration of the midbrain in the form of a uniform kind of sheet of cells along with the neural crest based cells and this actually emerges from the hindbrain as well as from the trunk based regions that further migrate in a elongated as well as segmented form. For instance, neural crest cells of the trunk very firmly pass through the rostral, but on the same side not through the caudal. Along with this the interaction that actually occurred after being interacted with the tissues during the migration process very firmly affects as well as influence this segmental based migration system. For instance, the mesoderm based somites very firmly dictate the proper segmental based migration of the trunk based neural crest cells and on the same side the otic placode as a matter of fact appears in order to attract the hindbrain based neural crest cells. Although very little information is highlighted regarding the molecular based underlying kind of a migration, thus various patterns of the gene based expression in the hindbrain are assumed to fully contribute towards the segmental based arrangement of the neural crest cells. Along with this, the neural crest cells carries on with an integrin based receptors that as a matter of fact termed as an important phenomenon in order to possess a proper interaction with the extra cellular matrix based molecules that as a matter of fact are present in their surroundings (Douarin & kalcheim, 1999, p.300).

Neural crest cells are as a matter of fact termed as a transient as well as a multipotent kind of a migration based cell population that is termed as a unique as well as a different one and the process is actually to vertebrates that as a result further give rise to a very broad as well as to a diverse cell kind of a lineage that actually comprises of melanocytes along with craniofacial as well as cartilage bone with some smooth kind of muscles as well (Serbedzija, 1991, p.600).

After the process of gastrulation, the neural crest based cells are further rectified at the plain border of those neural plated as well as at the non neural based ectoderm as well. During the process of neurulation, the neural plate ...