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Bcr/abl interfere with falcon anemia The t(9;22)(q34;q11) is detected in 95% of CML and 20–30% of adult ALL. CML is a myeloproliferative syndrome. In contrast, Ph+-ALL is an acute disease characterized by blasts blocked at the pre-lymphatic...
Chamary and Hurst. Analysis Chamary and Hurst anlysed in the article “The price of silent mutations” is that silent mutations are DNA mutations that do not result in a change to the amino acid sequence of a protein. They may occur in a non-...
human and cellular organisms is made of ribonucleic acid and deoxyribonucleic acid . Scientists are concerned with determining the series of genome that forms the DNA and RNA sequentials. In human genome project, scientists are concerned wi...
DNA is a very large molecule, made up of smaller units called nucleotides that are strung together in a row, making a DNA molecule thousands of times longer than it is wide. Each nucleotide has three parts: a sugar molecule, a phosphate mol...
virus type 1 (HSV-1), the major viral transcript that is detected is the latency-associated transcript (LAT) 2-kb intron. This intron is excised from a larger (10 kb) primary transcript. Infection of cells with HSV expressing LATs showed t...
additional in-frame exon A new alternative splice variant of BRCA1 containing an additional in-frame exon Introduction Breast cancer is the most common cancer affecting women in the Western world. During the past decade, a number of genes h...
tyrosine kinase that transduces signals, especially those triggered by hematopoietic growth factors such as erythropoietin, in normal and neoplastic cells. In March and April 2005, four groups of investigators reported finding an acquired ...