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implicated in the pathogenesis of numerous diseases including cancer. Increased formation of inflammatory cytokines such as TNF-a, IL-1ß and others has been described in the pathophysiology of degenerative diseases, infections and drug-indu...
mitochondrial dysfunction and cancerous infection was made as early as 1930, when Otto Warburg first hypothesized that the expanded rates of aerobic glycolysis which he discerned in a kind of tumor cell kinds might be due to an weakened re...
Parkinson’s disease These findings suggest that Parkinson's disease, like other neuro degenerative diseases including Alzheimer's, may start and progress due to abnormal aggregation and accumulation of proteins within the brain. What gets t...
Reichard and Bianchi (2006), Mitochondrial DNA Depletion and Thymidine Phosphate Pool Dynamics in a Cellular Model of Mitochondrial Neurogastrointestinal Encephalomyopathy, The Journal of Biological Chemistry Vol. 281, NO. 32, pp. 22720–227...
body part dysfunction syndrome (MODS) are foremost determinants of morbidity and death in the intensive care unit. Recently mitochondrial dysfunction has been suggested as a key early cellular happening in critical illness. A increasing bo...
phylogenies established on ribosomal RNA, three amitochondriate protist lineages, Microsporidia, Metamonada (comprising of diplomonads) and Parabasala (comprising of trichomonads), are the initial subsidiaries of the eukaryotic hierarchy. ...
is for Dan. Not because he's a fine upstanding soldier who sees life in a whole new perspective. Au contrair. Dan doesn't know how to play in the sandbox - and I do not mean the one where everyone in a man-dress takes chai breaks in betwee...